Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
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Our new Crystal clear+ tissue clearing system is the only technique that delipidates samples without any transform in morphology and with minimal impact on structural integrity.
Megatome is a vibrating microtome made to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue injury and data reduction.
Antibodies may possibly consider weeks to diffuse via only a few millimeters of tissue, having a steep labeling gradient from surface area to core.
Megatome is made for accuracy: the blade vibrates at a higher frequency and larger amplitude range than other microtomes, and features a distinctive deflection Manage mechanism.
Clone the venture or grab the most up-to-date launch. Running the utility will vary a tiny bit determined by how you retrieve the venture.
Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them thoroughly clear. This permits light penetration into your megatomi.com sample and makes certain the acquisition of substantial-resolution, in-concentrate image facts.
Megatome is a novel microtome that enables for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue hurt and information decline.
It’s time to update your microtome to Megatome. With accurate significant-frequency slicing for an unmatched selection of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied purposes.
Absolutely delipidate complete mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing package.
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Either obtain a launch or create a distribution zip as outlined over. Unzip the archive to your wished-for place.
Leverage the Obvious+ tissue clearing system, along with eFLASH and patented stochastic electrotransport technologies, to swiftly crystal clear and label full organs. Key highlights and attributes incorporate:
Our novel Protect tissue preservation system forms intramolecular bonds making use of polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.